In this episode, Jonathan Eisen compares a random DNA sequence fragment to a fossil bone from an archaeological dig and explains how to figure out what organism it probably came from.
Jonathan Eisen talked to Tools of Science about his research in both metagenomics and phylogenomics.
He explains the relationship between the two before describing studies on the microbiome of the Koala (because Chlamydia).
What else is he up to?
In addition to new methods for next generation sequencing analysis, he’s taking an evolutionary approach to analyzing DNA sequence data and to deciding what data sets are needed to fill in gaps in the tree of life.
We were curious to know:
-How do you get enough DNA from uncultured organisms for sequencing?
-How do you select which organisms you should sequence?
-And how do you confidently assemble individual genomes from a mixed environmental sample?
Tools of Science mentioned in this episode:
Want to see more videos like this? Contact us and tell us who we should interview. What do you want to know?
We’ve got more interviews with scientists talking about their work and the amazing technology that makes it possible on the way.
Leave a comment below and tell us what you think. What would like to see more of?